Manel Almela Selected Research

Cloxacillin (Tegopen)

12/2021	Effectiveness of vancomycin plus cloxacillin compared with vancomycin, cloxacillin and daptomycin single therapies in the treatment of methicillin-resistant and methicillin-susceptible Staphylococcus aureus in a rabbit model of experimental endocarditis.
12/2020	Cloxacillin or fosfomycin plus daptomycin combinations are more active than cloxacillin monotherapy or combined with gentamicin against MSSA in a rabbit model of experimental endocarditis.
1/2018	The Combination of Daptomycin and Fosfomycin Has Synergistic, Potent, and Rapid Bactericidal Activity against Methicillin-Resistant Staphylococcus aureus in a Rabbit Model of Experimental Endocarditis.
6/2014	Effect of vancomycin minimal inhibitory concentration on the outcome of methicillin-susceptible Staphylococcus aureus endocarditis.

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Manel Almela Research Topics

Disease

20	Endocarditis 01/2022 - 07/2007
15	Infections 01/2020 - 06/2003
12	Sepsis (Septicemia) 01/2019 - 03/2008
9	Bacteremia 01/2020 - 01/2008
5	Shock 10/2016 - 11/2006
4	Septic Shock (Toxic Shock Syndrome) 01/2018 - 08/2008
3	Neoplasms (Cancer) 11/2016 - 05/2006
3	Fever (Fevers) 02/2015 - 08/2004
3	Body Weight (Weight, Body) 05/2013 - 07/2007
2	Pneumonia (Pneumonitis) 01/2017 - 04/2006
2	Neutropenia 02/2015 - 05/2006
2	Staphylococcal Infections 06/2014 - 01/2009
2	Fibrosis (Cirrhosis) 09/2012 - 09/2011
1	Ischemic Stroke 01/2018
1	Hemorrhage 01/2018
1	Pneumococcal Pneumonia 01/2017
1	Embolism (Embolus) 11/2016
1	Colorectal Neoplasms (Colorectal Cancer) 11/2016
1	Heterotopic Ossification (Ectopic Ossification) 01/2011
1	Foreign Bodies (Foreign Body) 01/2009
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 03/2008
1	Necrosis 03/2008
1	Fungemia 05/2006
1	Candidemia 05/2006
1	Persistent Infection 06/2005
1	Febrile Neutropenia 08/2004
1	Mycoses (Diseases, Fungus) 08/2004
1	Aspergillosis 04/2004

Drug/Important Bio-Agent (IBA)

19	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 06/2003
10	Vancomycin FDA LinkGeneric 12/2021 - 07/2007
7	Daptomycin FDA Link 12/2021 - 07/2008
5	Methicillin (Metin)FDA Link 12/2021 - 01/2009
5	GlycopeptidesIBA 12/2014 - 06/2003
4	Cloxacillin (Tegopen)FDA Link 12/2021 - 06/2014
4	Carbapenems (Carbapenem Antibiotics)IBA 10/2017 - 11/2006
3	Gentamicins (Gentamicin)FDA LinkGeneric 12/2020 - 01/2018
3	Ampicillin (Omnipen)FDA LinkGeneric 01/2019 - 01/2009
3	Penicillins (Penicillin)FDA Link 01/2019 - 09/2011
2	Fosfomycin FDA Link 12/2020 - 01/2018
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2020 - 11/2016
2	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2019 - 01/2009
2	LactamsIBA 10/2017 - 01/2016
2	CoagulaseIBA 01/2015 - 01/2009
2	cyclo(Arg-Pro) (CI 4)IBA 06/2014 - 09/2012
2	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2008 - 01/2008
1	IceIBA 01/2022
1	Hexachlorobenzene (HCB)IBA 11/2018
1	Polyvinyl Chloride (PVC)IBA 11/2018
1	Amoxicillin (Wymox)FDA LinkGeneric 01/2017
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	Biomarkers (Surrogate Marker)IBA 01/2017
1	thiamine triphosphorate (TTP)IBA 01/2017
1	N 30IBA 11/2016
1	Ertapenem (Invanz)FDA Link 01/2016
1	Third Generation CephalosporinsIBA 02/2015
1	Linezolid (Zyvox)FDA Link 12/2014
1	QuinolonesIBA 09/2011
1	AntigensIBA 05/2010
1	AminoglycosidesIBA 01/2009
1	C-Reactive ProteinIBA 03/2008
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2008
1	Interleukin-6 (Interleukin 6)IBA 03/2008
1	telavancin FDA Link 07/2007
1	LipoglycopeptidesIBA 07/2007
1	Cephalosporins (Cephalosporin Antibiotics)IBA 11/2006
1	Erythromycin (Erycette)FDA LinkGeneric 12/2004
1	telithromycin (Ketek)FDA Link 12/2004
1	ProcalcitoninIBA 08/2004
1	beta-LactamsIBA 06/2003
1	Rifampin (Rifampicin)FDA LinkGeneric 06/2003

Therapy/Procedure

20	Therapeutics 12/2021 - 10/2003
5	Catheters 11/2018 - 05/2006
2	Length of Stay 12/2011 - 09/2011
2	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2011 - 06/2005
2	Artificial Respiration (Mechanical Ventilation) 08/2008 - 01/2008
2	Hip Prosthesis 06/2005 - 06/2003
1	Thrombectomy 01/2018
1	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 11/2016
1	Central Venous Catheters 09/2011
1	Organ Transplantation 09/2011
1	Reoperation 01/2011
1	Prostheses and Implants (Prosthesis) 01/2011
1	Infusion Pumps (Infusion Pump) 07/2007
1	Kidney Transplantation 11/2006
1	Parenteral Nutrition 05/2006
1	Stem Cell Transplantation 08/2004
1	Hematopoietic Stem Cell Transplantation 04/2004
1	Duration of Therapy 06/2003
1	Arthroplasty 06/2003
1	Debridement 06/2003
1	Drug Therapy (Chemotherapy) 06/2003